Vitamin D Level in Multiple Sclerosis Patients. Could Vitamin D Level Be Routine Investigation for Multiple Sclerosis Patients?

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Could vitamin D be the answer to multiple sclerosis?

Clinical and pathological studies would suggest that multiple sclerosis is a heterogeneous disease with individual patients varying dramatically in the extent of inflammatory change and axonal loss [1]. Relapses and inflammation appear to be due to an immune system in overdrive with the oligoden-drocyte as a possible primary target of what most are agreed is an autoimmune process [2]. Whilst ax...

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vitamin d and multiple sclerosis.

multiple sclerosis (ms) is a chronic demyelinating disease and also is one of the most common disabling neurological disorders in young and middle-aged adults. the main pathogenesis of ms has long been thought to be an immune mediated disorder of the central nervous system. the function of the immune system is under the influence of vitamin d which as a modulator of immune response could play a...

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The Association of Vitamin D Receptor Gene BsmI Polymorphism with Multiple Sclerosis in Iranian Patients

Background & Aims: 1,25-dihydroxyvitamin D3 (1,25 (OH)2 D3), the biologically active form of vitamin D, exerts an immunosuppressive effect through binding to its specific nuclear receptor. The present case-control study was done to examine the possible association of BsmI polymorphism in vitamin D receptor gene (VDR gene) with severity of multiple sclerosis (MS). Methods: 267 Iranian patients w...

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Vitamin D and multiple sclerosis

Multiple sclerosis (MS) is a chronic demyelinating disease and also is one of the most common disabling neurological disorders in young and middle-aged adults. The main pathogenesis of MS has long been thought to be an immune mediated disorder of the central nervous system. The function of the immune system is under the influence of vitamin D which as a modulator of immune response could play a...

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Vitamin D and multiple sclerosis.

The hypothesis that adequate vitamin D nutrition can contribute to the prevention of multiple sclerosis (MS) was originally proposed to explain the geographical distribution of MS, but only recently has the relation between various measures of vitamin D (eg, sun exposure, dietary sources, and serum concentrations of 25-hydroxyvitamin D) and risk of developing MS been rigorously investigated. Ov...

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ژورنال

عنوان ژورنال: Neuroscience and Medicine

سال: 2014

ISSN: 2158-2912,2158-2947

DOI: 10.4236/nm.2014.55023